Breakthrough in Morning Sickness Raises Hopes for a Potential Cure

Pregnant Women Morning Sickness

About 80% of pregnant women suffer from morning sickness that includes nausea and vomiting during their trimester. The recent findings related to the morning sickness have given hope to such ladies to get rid of this issue.

The scientists associated with this research have found the major cause that leads to such conditions in pregnant women.

Since the reason was found, it has opened the doors to the possibilities of finding effective cures to get through this condition.

Marlena Fejzo, who is an assistant professor at the University of Southern California’s Keck School of Medicine, wrote a paper related to women’s pregnancy and its nuances.

In the paper, she reveals that morning sickness is caused by the hormones that the fetus produces as they increase the levels of certain hormones in the body. 

She also says that the level of the GDF15 hormone is usually lower in women, and they experience a sudden surge in that hormone during the first trimester.

In such cases, the women suffer from nausea and vomiting conditions as it somewhat balances the hormone levels.

What The Research And Recent Study Revealed?

The research suggests that a sudden increase in GDF15 hormones in the body causes morning sickness. However, this can be managed through home remedies and medications.

But there is a rare case of hyperemesis gravidarum (HG) in which, along with the condition of morning sickness, women go through weight loss and dehydration.

One such case was reported to be of Princess of Wales, Catherine, who falls under the category of the remaining 2% of women who suffer from HG and are treated at a hospital to cure the condition.

Before the recent discovery, the underlying causes of morning sickness were unclear, and it was hard to manage the condition as there were restrictions and fear of using medicines during the ongoing pregnancy.

As stated by Charlotte Howden, who is the chief executive of the charity Pregnancy Sickness Support, women are suggested to eat a little often to get through this condition.

She further reveals that when she was hospitalized several times during her pregnancy, she often had a thought if it was her actions that were wrong.

Research About Pregnant Women Morning Sickness

What Was The Reason Behind The Beginning Of The Research?

Several women have been through this condition all these years, but no one ever took any initiative to find out the reasons. 

However, the research was initiated after Princess Catherine suffered from this condition, as no one was interested in finding out why women go through this before this news made its way to the headlines.

Since the reason behind the morning sickness was discovered, scientists speculate that if the levels of hormones are lowered, it can prevent the condition.

Other than that, the actions related to hormonal surge can be blocked so that there may be a reduction in the experience of morning sickness, nausea, and vomiting.

Also, they suggest that the women who are planning to conceive can be exposed to these hormones beforehand so that their bodies can get used to it before pregnancy.

If these are the possibilities, then there may be rare cases of morning sickness and HG in the future.

In the study, it was also found that the women who inherit beta thalassemia, which is a blood disorder, are likely to be protected from the condition of morning sickness.

This is because they are already prone or used to high levels of GDF15 hormones because of their chronic conditions.

So when the baby or fetus in the womb produces extra hormones, the mother takes it well, and thus, the body responds to this mutation appropriately.

Now that the cause of morning sickness has surfaced, scientists have suggested several ways to manage or prevent the condition.

Among all, the most effective way that seems to work well is the “priming,” i.e., prior exposure to the hormones. However, the question of whether women with a previous history of HG can respond to priming well or not remains a mystery.

Now that the most popular case of HG has made it to the headlines due to Princess Catherine, scientists are continuing the research to find out the next steps and strategies to deal with this condition.

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